NEBExpress Salt Active Nuclease, GMP Grade is a recombinant, engineered broad-specificity nuclease, designed to leverage high salt conditions to degrade nucleic acids in protein, adeno-associated virus (AAV), and biopharmaceutical manufacturing workflows for easier and more complete removal of these impurities. NEBExpress Salt Active Nuclease, GMP Grade is manufactured according to New England Biolabs’ GMP-grade* quality standards for stringent quality documentation and manufacturing needs. NEBExpress Salt Active Nuclease, GMP Grade is up to 2X more active than other nucleases at high salt to enable increased productivity and reduce costs. This GMP-grade enzyme is formulated at high concentration and activity to minimize sample dilution. NEBExpress Salt Active Nuclease, GMP Grade degrades all forms of DNA and RNA at a broad range of salt concentrations, with optimal activity at 500 mM NaCl/KCl.